Lever arm extension of myosin VI is unnecessary for the adjacent binding state

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Lever arm extension of myosin VI is unnecessary for the adjacent binding state

Myosin VI is a processive myosin that has a unique stepping motion, which includes three kinds of steps: a large forward step, a small forward step and a backward step. Recently, we proposed the parallel lever arms model to explain the adjacent binding state, which is necessary for the unique motion. In this model, both lever arms are directed the same direction. However, experimental evidence ...

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ژورنال

عنوان ژورنال: BIOPHYSICS

سال: 2015

ISSN: 1349-2942

DOI: 10.2142/biophysics.11.47